746-6 Myocardial Stretch Preconditions Isolated Working Rat Heart
نویسندگان
چکیده
منابع مشابه
Glutamine cycling in isolated working rat heart.
To what extent does glutamine turnover keep pace with oxidative metabolism in the rat heart? To address this question, the following groups of substrates were presented to the isolated, working rat heart: 1) glucose (5 mM), insulin (40 microU/ml), and [2-13C]acetate (5 mM; high workload, n = 5); 2) pyruvate (2.5 mM) and [2-13C]acetate (5 mM; normal workload, n = 5); or 3) propionate (1 mM) and ...
متن کاملPreferential oxidation of glycogen in isolated working rat heart.
We tested the hypothesis that glycogen is preferentially oxidized in isolated working rat heart. This was accomplished by measuring the proportion of glycolytic flux (oxidation plus lactate production) specifically from glycogen which is metabolized to lactate, and comparing it to the same proportion determined concurrently from exogenous glucose during stimulation with epinephrine. After prela...
متن کاملMyocardial contractility of the isovolumetrically beating isolated rat heart.
Several indexes of myocardial contractility have been proposed to assess ventricular function in the isovolumetrically beating isolated heart. However, the conclusions reached on the basis of these indexes may be influenced by ventricular geometry rather than contractility itself. The objective of the present study was to assess the performance of widely used contractility indexes in the isovol...
متن کاملFasting in vivo delays myocardial cell damage after brief periods of ischemia in the isolated working rat heart.
To assess the effects of fasting on recovery of function and exogenous glucose metabolism after 15 minutes of total ischemia, we perfused isolated working rat hearts from fed and fasted animals. Hearts were perfused in a recirculating system with bicarbonate buffer containing glucose (10 mM). Mechanical performance, release of marker proteins for ischemic membrane damage (lactate dehydrogenase,...
متن کاملChem. Pharm. Bull. 52(6) 739—746 (2004)
compounds from South American medicinal plants, we became interested in medicinal plants belonging to the genus Maytenus (Celastraceae). The plants of this genus are widely used in folk medicine in South America and are rich sources of terpenoids including dihydro-b-agarofuran sesquiterpenes, highly oxidized friedelane triterpenes, and several types of triterpene dimers. Among these, triterpene...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1995
ISSN: 0735-1097
DOI: 10.1016/0735-1097(95)92247-3